Related Experiment Video
Updated: May 5, 2026
Author Spotlight: Establishing a Practical and Cost-Effective Protocol for Corneal Sensitivity Testing in Clinical Settings
Published on: August 2, 2024
Corneal impairment in a patient with type 2 distal arthrogryposis
Jose L Güell1, Paula Verdaguer, Daniel Elies
1Cornea and Refractive Surgery Unit (J.L.G., P.V., D.E., O.G., F.M.), Instituto de Microcirugia Ocular, Barcelona, Spain; and Department of Ophthalmology (J.L.G., P.V., D.E., O.G., F.M.), Universitat Autònoma de Barcelona, Barcelona, Spain.
Objective:
Case report of a 7-year-old male patient, diagnosed with idiopathic progressive corneal alteration developed within a period of 6 months.
Methods:
Description of type 2 distal arthrogryposis affecting hands and feet, a bilateral, congenital hearing loss, alterations such as keloid-like scarring, congenital heart disease, and cryptorchidism with no relevant family history.
Results:
Corrected visual acuity in the right eye (RE) was 0.5 and in the left eye was 1 and, in addition to that, a bilateral corneal subepithelial fibrosis that was denser in the RE without neovessels and no signs of inflammatory activity.
Conclusion:
This is the first publication relating arthrogryposis with corneal affectation, probably because of a collagen anomaly characteristic in these patients.
