Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies II: Ultrasonography01:24

Imaging Studies II: Ultrasonography

924
IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
924

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cellular, electrophysiological and behavioral improvements in a mouse model of Rett syndrome following gene therapy combined with focused ultrasound-mediated blood-brain barrier opening.

Experimental neurology·2026
Same author

Focused acoustic vortex-mediated targeted aggregation of engineered bacteria for in situ antibody production to enhance immunotherapy.

Acta biomaterialia·2026
Same author

Combined Docetaxel-Loaded Perfluorocarbon Nanodroplets with Ultrasound-Mediated Blood-Brain Barrier Disruption for Effective Glioblastoma Treatment in Mice Model.

International journal of nanomedicine·2026
Same author

Shifting the paradigm of PSMA delivery in prostate cancer for internal radiotherapy: An innovative ultrasound-mediated approach.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026
Same author

Targeted photodynamic therapy for pancreatic cancer: recent innovations from fundamentals to <i>in vivo</i> and clinical applications (2020-2025).

Chemical communications (Cambridge, England)·2026
Same author

Liver Stiffness Characterization of OGT<sup>LKO</sup> Mouse Model of Progressive Liver Fibrosis.

Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine·2025

Related Experiment Video

Updated: May 5, 2026

Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time
09:56

Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time

Published on: November 4, 2014

10.3K

Dual-frequency transducer for nonlinear contrast agent imaging.

Axel Guiroy, Anthony Novell, Erling Ringgaard

    IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
    |December 4, 2013
    PubMed
    Summary

    This study introduces a novel dual-element transducer for enhanced microbubble imaging. The new design successfully detects high-frequency nonlinear components, improving contrast agent imaging sensitivity and resolution.

    More Related Videos

    Dual Raster-Scanning Photoacoustic Small-Animal Imager for Vascular Visualization
    07:14

    Dual Raster-Scanning Photoacoustic Small-Animal Imager for Vascular Visualization

    Published on: July 15, 2020

    3.5K
    Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
    17:16

    Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

    Published on: December 9, 2010

    12.3K

    Related Experiment Videos

    Last Updated: May 5, 2026

    Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time
    09:56

    Universal Hand-held Three-dimensional Optoacoustic Imaging Probe for Deep Tissue Human Angiography and Functional Preclinical Studies in Real Time

    Published on: November 4, 2014

    10.3K
    Dual Raster-Scanning Photoacoustic Small-Animal Imager for Vascular Visualization
    07:14

    Dual Raster-Scanning Photoacoustic Small-Animal Imager for Vascular Visualization

    Published on: July 15, 2020

    3.5K
    Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
    17:16

    Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

    Published on: December 9, 2010

    12.3K

    Area of Science:

    • Medical Imaging
    • Biomedical Engineering
    • Acoustics

    Background:

    • Microbubble-based contrast imaging relies on detecting nonlinear components.
    • Current limitations in transducer sensitivity and bandwidth hinder the detection of high-order harmonics (3rd-5th).

    Purpose of the Study:

    • To develop a novel dual-element transducer for improved high-frequency nonlinear contrast imaging.
    • To overcome the limitations of existing transducers in detecting high-order harmonics from microbubbles.

    Main Methods:

    • Designed a transducer with a 4 MHz low-frequency (LF) transmit element and a 14 MHz high-frequency (HF) receive element.
    • Fabricated the transducer using lead zirconate titanate (PZT) paste and commercial PZT, with a porous PZT backing.
    • Characterized piezoelectric elements and performed hydrophone measurements to assess electroacoustic responses and radiation patterns, demonstrating a 70% bandwidth for the HF element.

    Main Results:

    • The fabricated HF transducer exhibited a large bandwidth (70% at -3 dB).
    • Successfully detected microbubble harmonic components up to the sixth harmonic.
    • Acquired images from a flow phantom, showcasing the transducer's potential for high-frequency nonlinear contrast imaging.

    Conclusions:

    • The proposed dual-element transducer design enables sensitive detection of high-order nonlinear components from microbubbles.
    • This advancement offers significant potential for high-frequency nonlinear contrast imaging applications.
    • The simple fabrication process and demonstrated performance highlight the transducer's practical utility.