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Negative symptoms mediate the influence of theory of mind on functional status in schizophrenia
Urvakhsh Meherwan Mehta1, Jagadisha Thirthalli, Channaveerachari Naveen Kumar
1Department of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, 560029, India, Urvakhsh@gmail.com.
Abstract:
We aimed to assess the relationship between social cognition, neurocognition, negative symptoms and functional status in a homogeneous schizophrenia patient group remitted from positive symptoms. Sixty patients underwent assessments of social and neurocognition dimensions recommended by expert panels. A blind rater assessed their functional status. Second order theory of mind (ToM) and negative symptoms had significant correlations with functional status. A bootstrapping analysis used to test for specific mediation models revealed that the effect of second order ToM on functioning was mediated by negative symptoms. Future studies should examine if targeted remediation of ToM improves negative symptoms and thus functioning.
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