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Updated: May 5, 2026

Multimodal Imaging and Spectroscopy Fiber-bundle Microendoscopy Platform for Non-invasive, In Vivo Tissue Analysis
Published on: October 17, 2016
Narrow band 3 × 3 Mueller polarimetric endoscopy
Ji Qi1, Menglong Ye, Mohan Singh
1Hamlyn Centre for Robotic Surgery, Institute of Global Health Innovation, Imperial College London, Exhibition Road, London SW7 2AZ, UK ; Department of Surgery and Cancer, Imperial College London, Exhibition Road, London SW7 2AZ, UK.
None:
Mueller matrix polarimetric imaging has shown potential in tissue diagnosis but is challenging to implement endoscopically. In this work, a narrow band 3 × 3 Mueller matrix polarimetric endoscope was designed by rotating the endoscope to generate 0°, 45° and 90° linearly polarized illumination and positioning a rotating filter wheel in front of the camera containing three polarisers to permit polarization state analysis for backscattered light. The system was validated with a rotating linear polarizer and a diffuse reflection target. Initial measurements of 3 × 3 Mueller matrices on a rat are demonstrated, followed by matrix decomposition into the depolarization and retardance matrices for further analysis. Our work shows the feasibility of implementing polarimetric imaging in a rigid endoscope conveniently and economically in order to reveal diagnostic information.

