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Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

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Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
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Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
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Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
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A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
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Osteoarticular tuberculosis-a three years' retrospective study.

Arathi N1, Faiyaz Ahmad, Najmul Huda

  • 1Associate Professor,Department of Pathology, Teerthanker Mahaveer Medical College and Research Centre , Moradabad, U.P., India .

Journal of Clinical and Diagnostic Research : JCDR
|December 4, 2013
PubMed
Summary

This study on osteoarticular tuberculosis found that biopsy is crucial for diagnosis, especially in resource-limited settings. Early clinical suspicion and appropriate investigation of musculoskeletal TB lead to effective treatment and good patient outcomes.

Keywords:
Bone and joint TB (BJTB)Extrapulmonary TB (EPTB)Osteoarticular tuberculosisPott’s spine

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The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
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The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
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Area of Science:

  • Orthopedics
  • Pathology
  • Infectious Diseases

Background:

  • Extrapulmonary tuberculosis (TB) affects various organs, including the musculoskeletal system, causing significant functional impairment.
  • Musculoskeletal TB presents with variable symptoms, commonly pain and swelling.
  • Diagnosis involves imaging, histopathology, bacteriology, and PCR, with multidrug antitubercular chemotherapy as the primary treatment.

Purpose of the Study:

  • To analyze biopsy-diagnosed osteoarticular TB cases.
  • To correlate microscopic patterns, microbiological results, and clinical/radiological features.
  • To evaluate the response to antitubercular therapy (ATT).

Main Methods:

  • A retrospective study of 16 cases diagnosed with bone and/or joint TB over 3 years.
  • Data collected included clinical information, laboratory and microbiological investigations.
  • Biopsy samples were stained (Ziehl-Neelsen, PAS) and examined for microscopic features.

Main Results:

  • The average age of patients was 23.6 years, with pain and swelling being the most common symptoms.
  • The knee joint was most frequently involved (7 cases), followed by the spine and ankle.
  • Epithelioid granulomas were present in all cases (necrotizing in 11); Acid-Fast Bacilli (AFB) were positive in only 4 cases.

Conclusions:

  • Biopsy diagnosis of osteoarticular TB is vital, particularly in resource-limited settings.
  • Histopathological examination aids diagnosis and guides management of musculoskeletal TB.
  • ATT initiated in 12 cases showed a good treatment response.