Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Prevention02:59

Cancer Prevention

6.5K
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
6.5K
Cancer Prevention02:59

Cancer Prevention

2.6K
2.6K
The Tumor Microenvironment02:17

The Tumor Microenvironment

6.3K
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
6.3K
The Tumor Microenvironment02:17

The Tumor Microenvironment

2.7K
2.7K
Types of Toxins01:36

Types of Toxins

3.7K
Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...
3.7K
Mutagenicity and Carcinogenicity01:25

Mutagenicity and Carcinogenicity

2.0K
Mutagenicity and carcinogenicity refer to the ability of drugs to cause genetic defects and induce cancer, respectively. The International Agency for Research on Cancer (IARC) classifies agents into four groups based on their carcinogenic potential. Group 1 agents are known human carcinogens; group 2A agents are probably carcinogenic to humans; group 3 agents lack data to support their role in carcinogenesis; and group 4 includes agents for which data support that they are not likely to be...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

PRRC2A and BCL2L11 gene variants influence risk of non-Hodgkin lymphoma: results from the InterLymph consortium.

Blood·2012
Same author

Association of body mass index and risk of death from pancreas cancer in Asians: findings from the Asia Cohort Consortium.

European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP)·2012
Same author

Molecular epidemiology: linking molecular scale insights to population impacts.

IARC scientific publications·2012
Same author

Future perspectives on molecular epidemiology.

IARC scientific publications·2012
Same author

Previous lung diseases and lung cancer risk: a pooled analysis from the International Lung Cancer Consortium.

American journal of epidemiology·2012
Same author

Aromatic DNA adducts and number of lung cancer risk alleles in Map-Ta-Phut Industrial Estate workers and nearby residents.

Mutagenesis·2012

Related Experiment Video

Updated: May 5, 2026

Detecting Anastasis In Vivo by CaspaseTracker Biosensor
20:16

Detecting Anastasis In Vivo by CaspaseTracker Biosensor

Published on: February 1, 2018

8.8K

[Environment and cancer risk].

Paolo Boffetta1

  • 1The Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. paolo.boffetta@mssm.edu

La Revue Du Praticien
|December 5, 2013
PubMed
Summary
This summary is machine-generated.

Environmental pollutants like asbestos, radon, and arsenic in water are known carcinogens. While some pollutants are suspected, others like pesticides show no increased cancer risk, making environmental cancer research a priority.

More Related Videos

Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate DMBA-TPA
04:12

Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate DMBA-TPA

Published on: December 19, 2019

14.4K
Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats
09:36

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats

Published on: October 16, 2010

30.9K

Related Experiment Videos

Last Updated: May 5, 2026

Detecting Anastasis In Vivo by CaspaseTracker Biosensor
20:16

Detecting Anastasis In Vivo by CaspaseTracker Biosensor

Published on: February 1, 2018

8.8K
Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate DMBA-TPA
04:12

Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate DMBA-TPA

Published on: December 19, 2019

14.4K
Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats
09:36

Changes in Mammary Gland Morphology and Breast Cancer Risk in Rats

Published on: October 16, 2010

30.9K

Area of Science:

  • Environmental Health
  • Oncology
  • Toxicology

Context:

  • Environmental factors, including pollutants in air, water, and other media, are increasingly recognized for their role in cancer etiology.
  • Exposure to specific agents like asbestos, radon, secondhand tobacco smoke, diesel emissions, and arsenic in drinking water are established carcinogenic risks.
  • Other environmental factors such as outdoor air pollution and water chlorination byproducts are under investigation as potential carcinogens.

Purpose:

  • To review the evidence linking various environmental factors to cancer.
  • To differentiate between established carcinogens, suspected carcinogens, and factors with insufficient evidence of risk.
  • To highlight the importance of continued research into environmental causes of cancer.

Summary:

  • Established environmental carcinogens include asbestos, radon, secondhand smoke, diesel exhaust, and arsenic in drinking water.
  • Suspected carcinogens encompass outdoor air pollution and water chlorination byproducts.
  • Pesticides and electromagnetic fields (e.g., cell phones) currently lack sufficient evidence to link them to increased cancer risk.
  • Environmental factors contribute a limited proportion to the overall cancer burden in high-income countries.

Impact:

  • Environmental cancer research is crucial due to the involuntary nature of exposure and the potential for preventive interventions.
  • Identifying and mitigating environmental carcinogens can reduce the population's cancer risk.
  • This research informs public health policies and environmental regulations aimed at cancer prevention.