Cerebellar abscess caused by Listeria monocytogenes in a liver transplant patient

N Choudhury1, A B Khan, I Tzvetanov

  • 1Division of Transplantation, Department of Surgery, University of Illinois Hospital and Health Sciences System, Chicago, Illinois, USA.

Insights

Listeria monocytogenes, a rare cause of brain abscesses, can affect liver transplant recipients. This case highlights the importance of considering this pathogen for prompt diagnosis and treatment to prevent severe neurological damage.

Area of Science:

  • Infectious Diseases
  • Neurosurgery
  • Transplantation Medicine

Background:

  • Brain abscesses are infrequent but severe complications in transplant recipients.
  • Aspergillus is the predominant cause of post-transplant brain abscesses.
  • Bacterial involvement, excluding Nocardia, is uncommon in transplant-associated brain abscesses.

Observation:

  • A 52-year-old male liver transplant recipient developed a cerebellar abscess.
  • The abscess was caused by Listeria monocytogenes, an unusual pathogen in this context.
  • Symptoms included headache and vomiting three months post-transplantation.

Findings:

  • Cerebellar abscess (CA) diagnosed via CT and MRI.
  • Emergency surgery was performed due to mass effect.
  • The patient experienced an uncomplicated surgical recovery.

Implications:

  • This case represents the first reported instance of Listeria monocytogenes causing a cerebellar abscess after orthotopic liver transplantation (OLT).
  • Clinicians must maintain awareness of L. monocytogenes as a potential, albeit rare, cause of CA in OLT patients.
  • Prompt recognition and management are crucial to avert significant neurological sequelae.

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