Related Experiment Video

Updated: May 5, 2026

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness
05:51

Measuring the Carotid to Femoral Pulse Wave Velocity Cf-PWV to Evaluate Arterial Stiffness

Published on: May 3, 2018

17.8K

Relationship between inter-arm difference in systolic blood pressure and arterial stiffness in community-dwelling

Marco Canepa1, Yuri Milaneschi, Pietro Ameri

  • 1Longitudinal Studies Section, Translational Gerontology Branch, NIA/NIH, Baltimore, MD; Laboratory of Cardiovascular Sciences, Human Cardiovascular Studies Unit, NIA/NIH, Baltimore, MD; Department of Internal Medicine, University of Genova, Genova, Italy.

Journal of Clinical Hypertension (Greenwich, Conn.)
|December 5, 2013
PubMed

Insights

Significant inter-arm blood pressure difference (IADSBP) is linked to arterial stiffness. This study found higher carotid-femoral pulse wave velocity (CF-PWV) in older adults with IADSBP ≥10 mmHg, indicating increased arterial stiffness.

Area of Science:

  • Cardiovascular Medicine
  • Gerontology
  • Biomedical Engineering

Background:

  • A significant inter-arm difference in systolic blood pressure (IADSBP) is associated with adverse cardiovascular outcomes.
  • Arterial stiffness is a potential mediator of this association.

Purpose of the Study:

  • To investigate the relationship between significant IADSBP and arterial stiffness, measured by carotid-femoral pulse wave velocity (CF-PWV).

Main Methods:

  • Analysis of data from the Baltimore Longitudinal Study of Aging, including 1045 participants.
  • Assessment of IADSBP (≥10 mmHg) and CF-PWV at baseline and over an 8-year period.
  • Multivariate analyses to identify correlates of IADSBP and its association with CF-PWV.

Main Results:

  • Participants with IADSBP ≥10 mmHg exhibited significantly higher CF-PWV (8.2±2 vs 7.3±1.9, P=.002).
  • IADSBP ≥10 mmHg was significantly associated with higher CF-PWV cross-sectionally (OR, 1.19) and longitudinally (OR, 1.15).
  • Independent correlates of IADSBP included female sex, Caucasian race, higher BMI, diabetes, and lower HDL cholesterol.

Conclusions:

  • Significant IADSBP is associated with increased arterial stiffness in community-dwelling older adults.
  • Arterial stiffness may play a role in the cardiovascular risks associated with IADSBP.

More Related Videos

Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging06:08

Pulse Wave Velocity Testing in the Baltimore Longitudinal Study of Aging

Published on: February 7, 2014

16.8K
Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound10:08

Measuring Ascending Aortic Stiffness In Vivo in Mice Using Ultrasound

Published on: December 2, 2014

17.1K

Related Concept Videos

Special considerations while measuring blood pressure01:28

Special considerations while measuring blood pressure

When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
1.5K
Assessment of blood pressure in brachial artery(two-step method)01:23

Assessment of blood pressure in brachial artery(two-step method)

Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...
2.1K
Assessment of blood pressure in brachial artery(one-step method)01:15

Assessment of blood pressure in brachial artery(one-step method)

This procedural guide systematically measures blood pressure using an oscillometric digital sphygmomanometer, emphasizing accuracy, patient safety, and comfort.
Prepare for the Procedure:
1.4K
Pre-Procedural Guidelines for Assessing Blood Pressure01:10

Pre-Procedural Guidelines for Assessing Blood Pressure

Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the...
880
Sites for measuring blood pressure01:21

Sites for measuring blood pressure

Blood pressure measurement is a fundamental clinical procedure, providing crucial data for assessing cardiovascular health. Among the various sites for this measurement, the brachial and popliteal arteries are predominantly utilized due to their accessibility and the reliability of their readings. This lesson delves into the anatomical significance, methodology, and considerations of measuring blood pressure at these locations.
The Brachial Artery: Primary Site for Blood Pressure Measurement
3.9K
Assessing Blood pressure in the Leg01:11

Assessing Blood pressure in the Leg

Proper measurement of leg blood pressure is a critical skill for healthcare providers, ensuring precise and reliable readings. When performed correctly, this procedure informs patient care and enhances the efficacy of interventions. The following text outlines step-by-step guidelines to measure blood pressure in the leg, providing clarity and ease of understanding for practitioners.
Preparation:
17.9K