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Increased oxidative stress and xanthine oxidase activity in human ruptured cerebral aneurysms

Li Li1, Xinjian Yang, Gregory J Dusting

  • 1Department of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University; Beijing, China - fjiang@unimelb.edu.au.

The Neuroradiology Journal
|December 5, 2013
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A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
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