Related Experiment Video

Updated: Aug 15, 2026

A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status
07:08

A High Throughput, Multiplexed and Targeted Proteomic CSF Assay to Quantify Neurodegenerative Biomarkers and Apolipoprotein E Isoforms Status

Published on: October 20, 2016

Proteins as parameters in the discrimination between different blood-CSF barriers

G Keir, E J Thompson

    Journal of the Neurological Sciences
    |October 1, 1986
    PubMed

    Data on cerebrospinal fluid to serum concentration ratios for albumin, IgG and alpha 2-macroglobulin were analysed by groupings based on electrophoretic or clinical criteria. Statistically significant differences (P less than 0.01) were found for distinguishing up to three different blood-CSF barriers, when compared to normal barrier function.

    More Related Videos

    A Human Blood-Brain Interface Model to Study Barrier Crossings by Pathogens or Medicines and Their Interactions with the Brain07:52

    A Human Blood-Brain Interface Model to Study Barrier Crossings by Pathogens or Medicines and Their Interactions with the Brain

    Published on: April 9, 2019

    Quantitative Measurement of Intrathecally Synthesized Proteins in Mice08:23

    Quantitative Measurement of Intrathecally Synthesized Proteins in Mice

    Published on: November 29, 2019

    Related Concept Videos

    The Blood-brain Barrier00:49

    The Blood-brain Barrier

    Overview
    Physiological Barriers01:25

    Physiological Barriers

    Physiological barriers are semi-permeable cellular structures restricting drug diffusion into intracellular compartments and tissues. There are six types of physiological barriers: blood endothelial, cell membrane, blood-brain, blood-cerebrospinal fluid (CSF), blood-placenta, and blood-testis barriers.
    The blood endothelial barrier is the most porous of these. It allows all small ionized, un-ionized, and lipophilic molecules to pass through the endothelial lining into the interstitial space...