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[Cognitive disorders and their correction in patients with ischemic stroke]
Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|December 5, 2013
Summary
Long-term use of Cortexin in ischemic stroke patients improved cognitive function and motor skills. This cytoprotector drug helped minimize post-stroke cognitive impairment over a year.
Area of Science:
- Neurology
- Pharmacology
Background:
- Ischemic stroke (IS) frequently leads to cognitive impairment and motor deficits.
- Long-term recovery management is crucial for patients with IS.
- Cytoprotective neuropeptides offer potential therapeutic benefits.
Purpose of the Study:
- To evaluate the long-term effectiveness of Cortexin on cognitive status in IS patients.
- To assess the impact of Cortexin on motor recovery and cognitive function dynamics.
- To determine if Cortexin minimizes post-stroke cognitive impairment.
Main Methods:
- A one-year study involving 80 first-time IS patients.
- The main group (40 patients) received standard therapy plus Cortexin (10 mg/day for 10 days) at 3, 6, and 9 months.
- The control group (40 patients) received only basic and vascular therapy.
Main Results:
- Four courses of Cortexin over a year promoted regression of motor disorders.
- Cortexin stabilized and restored cognitive functions in IS patients.
- The treatment minimized the likelihood of post-stroke cognitive impairment.
Conclusions:
- Long-term, intermittent Cortexin administration is effective in managing IS recovery.
- Cortexin aids in both motor and cognitive rehabilitation post-ischemic stroke.
- This neuropeptide drug shows promise in reducing long-term cognitive deficits after stroke.
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