Related Experiment Video
Updated: May 5, 2026
09:35
Attaching Biological Probes to Silica Optical Biosensors Using Silane Coupling Agents
Published on: May 1, 2012
12.7K
The promotion of antimicrobial activity on silicon substrates using a "click" immobilized short peptide
Lin Wang1, Junjian Chen, Lin Shi
1National Engineering Research Center for Tissue Restoration and Reconstruction, South China University of Technology, Guangzhou 510006, China. imwangyj@163.com.
Chemical Communications (Cambridge, England)
|December 5, 2013
Abstract:
We demonstrated, for the first time, that the short antimicrobial peptide Tet213 could be conjugated onto the silicon surface by Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC). The modified surface exhibited excellent antimicrobial activity against S. aureus and E. coli, and low cytotoxicity to rat bone mesenchymal stem cells (rBMSCs).
