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Genetic Networks of Complex Disorders: from a Novel Search Engine for PubMed Article Database
Jae-Yoon Jung1, Dennis Paul Wall
1Harvard Medical School, Boston, MA;
Abstract:
Finding genetic risk factors of complex disorders may involve reviewing hundreds of genes or thousands of research articles iteratively, but few tools have been available to facilitate this procedure. In this work, we built a novel publication search engine that can identify target-disorder specific, genetics-oriented research articles and extract the genes with significant results. Preliminary test results showed that the output of this engine has better coverage in terms of genes or publications, than other existing applications. We consider it as an essential tool for understanding genetic networks of complex disorders.
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