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The effect of ketamine on posttonsillectomy pain in children: a clinical trial

Akbar Pirzadeh1, Mohammad-Ali Mohammadi, Sooreh Allaf-Akbari

  • 1Department of otorhinolaryngology, Ardabil University of Medical Sciences, Ardabil, Iran.

Iranian Journal of Otorhinolaryngology
|December 5, 2013
PubMed

Insights

Preoperative peritonsillar ketamine injection effectively reduced pain after tonsillectomy in children. This method provided significant postoperative pain relief without increasing complications.

Area of Science:

  • Anesthesiology
  • Pediatric Surgery
  • Pain Management

Background:

  • Tonsillectomy is a common procedure with significant postoperative pain.
  • Effective pain management is crucial for pediatric patients undergoing tonsillectomy.
  • Previous research on ketamine for postoperative analgesia after tonsillectomy yielded mixed results.

Purpose of the Study:

  • To evaluate the efficacy of preoperative peritonsillar ketamine injection for postoperative pain relief in children.
  • To compare pain scores and complication rates between ketamine and saline groups.

Main Methods:

  • A randomized controlled trial (RCT) involving sixty children aged 3-12 years.
  • Participants received either 1 mg/kg ketamine or normal saline via peritonsillar injection five minutes before tonsillectomy.
  • Pain was assessed using the Oucher Scale and CHEOPS; sedation was evaluated with the Wilson Sedation Scale.

Main Results:

  • The ketamine group showed a statistically significant reduction in postoperative pain scores compared to the control group.
  • Pain levels were lower in the ketamine group at two hours post-surgery.
  • No significant differences were observed in the incidence of nausea and vomiting between the groups.

Conclusions:

  • Peritonsillar ketamine injection administered preoperatively effectively reduces pain following tonsillectomy in children.
  • This intervention offers a safe method for managing post-tonsillectomy pain without adverse effects.
Abstract

Keywords:
ChildrenKetaminePostoperative painTonsillectomy

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