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The effect of adenotonsillectomy on pediatric nocturnal enuresis: a prospective cohort study
Mohammad Saeed Ahmadi1, Shahriar Amirhassani, Jalal Poorolajal
1Department of Otolaryngology & Head and Neck surgery, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran .
Insights
Adenotonsillar hypertrophy can cause childhood enuresis. Adenotonsillectomy (adenoid and tonsil removal) significantly improved or resolved bedwetting in over 85% of children studied.
Area of Science:
- Pediatric Otolaryngology
- Pediatric Urology
- Sleep Medicine
Background:
- Sleep disorders linked to adenotonsillar hypertrophy are a known cause of childhood nocturnal enuresis.
- Adenotonsillar hypertrophy can lead to primary and secondary enuresis in children.
Purpose of the Study:
- To investigate the efficacy of adenotonsillectomy in treating enuresis in children with adenotonsillar hypertrophy.
- To evaluate the impact of adenotonsillectomy on nocturnal enuresis resolution and improvement.
Main Methods:
- Prospective cohort study involving 97 children (aged 3-12) with adenotonsillar hypertrophy undergoing adenotonsillectomy.
- Data collected via questionnaire on enuresis incidents, type, and family history; follow-up for 3 months post-operation.
- Included urine analysis and comparison of pre- and post-operative bedwetting frequency.
Main Results:
- Of 97 children with pre-operative enuresis, 84 participated.
- Three months post-adenotonsillectomy, 60.7% experienced complete enuresis resolution, and 26.2% showed relative improvement.
- Enuresis persisted in 13.1% of children (P<0.001).
Conclusions:
- Adenotonsillectomy demonstrates significant potential for improving nocturnal enuresis in children with adenotonsillar hypertrophy.
- Further large-scale, multi-center randomized clinical trials are warranted to validate these findings.
Introduction:
Sleep disorder caused by adenotonsillar hypertrophy has been implicated as a cause of primary and secondary nocturnal enuresis in children. This study was conducted to investigate the effect of adenotonsillectomy on enuresis in children with adenotonsillar hypertrophy.
Materials And Methods:
This prospective cohort study was conducted in Hamadan City in Western Iran, from April 2010 to December 2011. Ninety-seven children aged 3 to 12 years with adenotonsillar hypertrophy who were admitted to Besat Hospital for adenotonsillectomy were evaluated. The primary outcome was the number of incidents of bedwetting (nocturnal enuresis) post-operation compared with pre-operation. Patients were followed-up for 3 months. Data were collected using a questionnaire regarding number of bedwetting incidents, type of enuresis (primary or secondary), and family history of enuresis, as well as results of urine analysis.
Results:
Of 420 children admitted for adenotonsillectomy, 97 had a positive history of preoperative enuresis, including 42 girls and 55 boys, with mean age of 48 months. The parents of 84 (86.6%) children agreed to participate in the study. Three months after adenotonsillectomy, enuresis had resolved completely in 51 (60.7%) children and had shown relative improvement in 22 (26.2%) children. Enuresis had not improved in the remaining 11 (13.1%) children (P<0.001).
Conclusion:
The results of this study indicate that adenotonsillectomy can improve enuresis in the majority of children with adenotonsillar hypertrophy. However, further evidence based on large multi-center randomized clinical trials is required to confirm these results.
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