Spontaneous coronary dissection in polycystic kidney disease

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Maxwell E Afari1, Abdullah Quddus, Manoj Bhattarai

  • 1Internal Medicine Resident at the Warren Alpert Medical School of Brown University (Memorial Hospital of Rhode Island).

Rhode Island Medical Journal (2013)
|December 5, 2013
PubMed

Insights

Spontaneous coronary artery dissection (SCAD) is rare in patients with autosomal dominant polycystic kidney disease. This case highlights the importance of considering SCAD in patients with polycystic kidney disease presenting with chest pain.

Area of Science:

  • Cardiology
  • Nephrology
  • Genetics

Background:

  • Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited disorder.
  • Hypertension is a frequent comorbidity in ADPKD patients.
  • Spontaneous coronary artery dissection (SCAD) is a non-atherosclerotic condition affecting coronary arteries.

Observation:

  • A 46-year-old woman with hypertension and ADPKD presented with chest pain.
  • Diagnostic catheterization revealed spontaneous coronary artery dissection (SCAD).

Findings:

  • SCAD should be considered in ADPKD patients experiencing angina pectoris.
  • Positive cardiac biomarkers in this context warrant investigation for SCAD.

Implications:

  • This case expands the understanding of SCAD associations.
  • Highlights the need for heightened cardiovascular awareness in ADPKD management.
  • Suggests potential screening or diagnostic considerations for SCAD in at-risk populations.

Keywords:
Polycystic kidney diseaseextra renalspontaneous coronary dissection

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