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Updated: May 5, 2026

Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE
Published on: August 16, 2024
[Hyperostosis frontalis interna and epilepsy]
M Winant1, T Richard, M Vanhaeverbeek
1ULB, C.H.U. de Charleroi, Site André Vésale, Montigny-le-Tilleul.
Abstract:
We have analysed the clinical history of a 48-year old female patient who has been admitted to hospital after an epileptic fit. The tomodensitometry examination has shown a hyperostosis frontalis interna. This condition is frequent and is characterized by a progressive thickening of the frontal bone internal table. The aetiology is unknown; the most probable hypothesis is a deterioration of the androgen-estrogen ratio. This woman suffers from epileptic fits for 40 years now but also from hereditary polycystic kidney disease and CREST syndrome. In this analysis, we have applied the principle of parcimony and we have examined the role played by the sexual hormones in these pathologies.
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