Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Whole Body Regeneration01:33

Whole Body Regeneration

3.6K
Regeneration is the process of restoring injured or lost tissues, organs, or body parts. While simpler organisms generally show greater ability to regenerate their whole body, few complex animals show similarly exceptional regeneration. For example, planarian flatworms have a unique regenerative potential making them a popular study organism among biologists to understand the mechanisms of whole body regeneration. Other organisms, such as hydra, also show extreme regeneration potential;...
3.6K
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

3.8K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
3.8K
Tissue Renewal without Stem Cells01:23

Tissue Renewal without Stem Cells

1.6K
After cellular or tissue damage, the resident stem cells present in the human body can locally repair and regenerate the damaged tissue or organ. However, even though some tissues do not have stem cells, they can repair and regenerate with the help of pre-existing cells. For example, beta cells of the pancreas and hepatocytes of the liver can divide to renew and regenerate the tissue. Here, both cell division and cell death are well regulated by homeostasis.
However, failure of such a system...
1.6K
Overview of Regeneration and Repair01:19

Overview of Regeneration and Repair

4.8K
Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...
4.8K
iPS Cell Differentiation01:22

iPS Cell Differentiation

2.2K
The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
2.2K
Induced Pluripotent Stem Cells01:13

Induced Pluripotent Stem Cells

22.9K
Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
22.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

REPLY: Is There an Intramyocardial "Purkinje" System in the Heart?

JACC. Clinical electrophysiology·2025
Same author

Healthspan-lifespan gap differs in magnitude and disease contribution across world regions.

Communications medicine·2025
Same author

MYL4 Identifies Intramural Anatomy of Purkinje Fibers in Human Hearts.

JACC. Clinical electrophysiology·2025
Same author

Maturation of human induced pluripotent stem cell-derived cardiomyocytes promoted by Brachyury priming.

Scientific reports·2025
Same author

Therapeutic effects of platelet-derived extracellular vesicles on viral myocarditis correlate with biomolecular content.

Frontiers in immunology·2025
Same author

Artificial intelligence powers regenerative medicine into predictive realm.

Regenerative medicine·2024

Related Experiment Video

Updated: May 5, 2026

Generation of Aligned Functional Myocardial Tissue Through Microcontact Printing
11:09

Generation of Aligned Functional Myocardial Tissue Through Microcontact Printing

Published on: March 19, 2013

10.5K

Regenerative medicine blueprint.

Andre Terzic1, C Michel Harper, Gregory J Gores

  • 1Center for Regenerative Medicine, Mayo Clinic , Rochester, Minnesota.

Stem Cells and Development
|December 6, 2013
PubMed
Summary

Regenerative medicine offers transformative treatments for various diseases and injuries. This field requires an interdisciplinary approach to advance scientific discoveries into clinical applications for better patient care.

Area of Science:

  • Regenerative medicine and its impact on future healthcare.
  • Advancements in regenerative technologies for structural repair and functional restoration.

Background:

  • Regenerative medicine presents significant potential for treating diverse diseases and conditions across all age groups.
  • Current medical and surgical practices are being revolutionized by emerging regenerative technologies.

Purpose of the Study:

  • To highlight the transformative potential of regenerative medicine in healthcare.
  • To outline a strategy for translating scientific advancements into clinical practice.

Main Methods:

  • The abstract describes a blueprint for regenerative medicine.
  • This blueprint emphasizes an interdisciplinary and patient-centered approach.
  • It focuses on optimizing the discovery-translation-application roadmap.

More Related Videos

Production of Autologous Platelet-Rich Plasma for Boosting In Vitro Human Fibroblast Expansion
08:34

Production of Autologous Platelet-Rich Plasma for Boosting In Vitro Human Fibroblast Expansion

Published on: February 24, 2021

2.8K
Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
10:24

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report

Published on: February 12, 2018

9.6K

Related Experiment Videos

Last Updated: May 5, 2026

Generation of Aligned Functional Myocardial Tissue Through Microcontact Printing
11:09

Generation of Aligned Functional Myocardial Tissue Through Microcontact Printing

Published on: March 19, 2013

10.5K
Production of Autologous Platelet-Rich Plasma for Boosting In Vitro Human Fibroblast Expansion
08:34

Production of Autologous Platelet-Rich Plasma for Boosting In Vitro Human Fibroblast Expansion

Published on: February 24, 2021

2.8K
Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
10:24

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report

Published on: February 12, 2018

9.6K

Main Results:

  • Regenerative medicine promises innovative solutions for unmet patient needs, including congenital diseases, trauma, and degenerative conditions.
  • The Mayo Clinic's regenerative medicine blueprint facilitates the advancement of science-supported medical practices.

Conclusions:

  • Regenerative medicine is poised to significantly improve patient outcomes by addressing a wide range of conditions.
  • An interdisciplinary, team-based strategy is crucial for realizing the full potential of regenerative medicine in clinical settings.