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Updated: May 5, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
[Bullous pemphigoid: a cutaneous disorder to be known in aging persons]
Samuel Perivier1, Laurence Toutous Trellu
1Service de gériatrie, HUG, 1211 Genève 14. samuel.perivier@hcuge.ch
Abstract:
Bullous pemphigoid is a rare autoimmune muco-cutaneous disorder involving particularly aged adults. Its incidence may be underestimated. Recent studies show the various clinical presentations that may delay diagnosis up to several years in absence of typical bullous presentation. Diagnosis such as skin adverse event or infection should be quickly eliminated and the autoimmunity confirmed with skin and blood immunology and pathology analysis. Any chronic pruritis or persisting blister in old people should lead to the diagnosis procedures of a bullous pemphigoid.
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