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Quantitative imaging biomarkers for the evaluation of cardiovascular complications in type 2 diabetes mellitus

Kai Lin1, Donald M Lloyd-Jones2, Debiao Li1

  • 1Department of Radiology, Northwestern University Feinberg School of Medicine, 737N Michigan Avenue, Suite 1600, Chicago, IL 60611, USA.

Journal of Diabetes and Its Complications
|December 7, 2013
PubMed

Insights

Cardiovascular imaging offers advanced methods to assess heart risks in older adults with type 2 diabetes (T2DM). Quantitative imaging biomarkers can personalize treatment and improve outcomes for T2DM patients facing cardiovascular disease.

Area of Science:

  • Cardiology
  • Radiology
  • Endocrinology

Background:

  • Type 2 diabetes mellitus (T2DM) is common in older adults and significantly increases cardiovascular disease (CVD) risk.
  • CVD is a primary cause of death and disability in T2DM patients.
  • Current T2DM treatments targeting traditional risk factors show controversial efficacy in recent trials.

Purpose of the Study:

  • To review state-of-the-art cardiovascular imaging techniques for T2DM.
  • To discuss the application of these techniques in clinical settings.
  • To highlight the potential of quantitative imaging biomarkers for risk stratification and therapy selection in T2DM.

Main Methods:

  • Review of current literature on multi-disciplinary cardiovascular imaging.
  • Comparison of various imaging modalities and their applications.
  • Focus on quantitative imaging biomarkers for assessing cardiovascular abnormalities.

Main Results:

  • Cardiovascular imaging provides quantitative assessment of morphological and functional cardiovascular abnormalities.
  • Advanced imaging techniques can detect and quantify cardiovascular disease burden.
  • Quantitative imaging biomarkers are emerging as valuable tools for risk stratification.

Conclusions:

  • Quantitative imaging biomarkers derived from advanced cardiovascular imaging can offer novel insights into cardiovascular risk in T2DM.
  • These biomarkers can aid in selecting optimal therapies and potentially reduce healthcare costs for T2DM patients.
  • Individualized measurements of cardiovascular disease burden are recommended for assessing treatment response in T2DM.
Keywords:
Cardiovascular complicationsImaging biomarkersT2DM

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