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Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Periodontal pathogens and respiratory diseases- evaluating their potential association: a clinical and
S Vadiraj1, Rashmita Nayak, Gopal Krishna Choudhary
1Reader, Department of Periodontics, PDU Dental College and Hospital, Solapur, Maharashtra, India,
Objective:
To evaluate whether any potential association exists between respiratory diseases such as chronic obstructive pulmonary disease (COPD) and periodontal health status clinically and or microbiologically.
Materials And Methods:
Fifty patients of COPD (test group) and 50 Patients without COPD (control group) were recruited for the study with more than 20 years of age with at least six natural teeth. All the patients were nonsmokers. Periodontal health was assessed by measuring clinical attachment loss (CAL) and gingival bleeding by using William's graduated periodontal probe. Microbiological evaluation was done by collecting sputum samples of the subjects with respiratory diseases to find out any periodontal pathogen in the lung fluid.
Result And Conclusion:
The results showed that the subjects with COPD had significantly more bleeding sites (i.e. >20%) and had more of the clinical mean attachment loss (2.84 ± 0.66) than those without COPD. On the basis of the observed results of the study, we can hypothesize that the risk for COPD appeared to be significantly elevated when attachment loss was found to be severe.
Clinical Significance:
It is conceivable that oral interventions that improve oral health status may prove to lower the severity of lung infection in susceptible populations.
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