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Published on: October 12, 2012
[Warfarin-related nephropathy: a case report]
L Zerah1, I Brochériou2, P Galichon3
1Urgences néphrologiques et transplantation rénale, hôpital Tenon, AP-HP, 4, rue de la Chine, 75020 Paris, France.
Introduction:
Warfarin-related nephropathy (WRN) is a newly recognized entity, which is characterized by the occlusion of renal tubules by red blood cells following glomerular hemorrhage in a patient overexposed to warfarin (international normalized ratio>3).
Case Report:
We report a 70-year-old man with no previous renal condition who developed WRN when his INR was>12. He did not fully recover his previous renal function.
Conclusion:
The diagnosis of WRN should be considered whenever INR exceeds 3 in patients exposed to warfarin, particularly in the presence of hematuria. Vitamin K is the only therapeutic option.
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