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Responses upon multiple administration of L-thyroxine in hens.

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Repeated L-thyroxine injections significantly altered enzyme activity and total protein in White Rock and Sussex hens, with notable differences observed between breeds. These findings highlight L-thyroxine

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Area of Science:

  • Comparative physiology
  • Avian endocrinology
  • Biochemistry

Background:

  • L-thyroxine plays a crucial role in avian metabolism and growth.
  • Understanding the impact of exogenous L-thyroxine on enzyme profiles is vital for poultry science.
  • Breed-specific responses to hormonal treatments can occur in poultry.

Purpose of the Study:

  • To investigate the effects of repeated L-thyroxine administration on blood plasma enzyme activities and total protein levels.
  • To compare the biochemical responses to L-thyroxine between White Rock and Sussex hen breeds.

Main Methods:

  • Repeated intramuscular injections of L-thyroxine were administered to White Rock and Sussex hens.
  • Blood plasma samples were collected and analyzed for total protein.
  • Enzyme activities including aldolase, alanine aminotransferase, aspartate aminotransferase, and alkaline phosphatase were measured.

Main Results:

  • Total protein levels significantly decreased in both hen breeds.
  • Aldolase activity increased in White Rock hens and delayed in Sussex hens. Alanine aminotransferase activity remained unchanged in White Rock hens but increased in Sussex hens.
  • Aspartate aminotransferase activity showed an initial increase in both breeds. Alkaline phosphatase activity increased in White Rock hens but decreased in Sussex hens, with significant inter-breed differences noted.

Conclusions:

  • Repeated L-thyroxine injections induce significant alterations in plasma enzyme activities and total protein levels in hens.
  • Distinct differences in biochemical responses to L-thyroxine were observed between White Rock and Sussex breeds.
  • These findings contribute to understanding the physiological impact of thyroid hormone supplementation in poultry.