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Antigenic Liposomes for Generation of Disease-specific Antibodies
Published on: October 25, 2018
Muscle-specific kinase antibody associated myasthenia gravis after bone marrow transplantation
Zeinab Heidarzadeh1, Seyyed-Asadollah Mousavi2, Vahid Reza Ostovan1
1Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Abstract:
Myasthenia gravis is a rare complication of bone marrow transplantation and graft versus host disease. We report a 30-year-old woman presented with oculobulbar and proximal limb weakness after allogeneic bone marrow transplantation for chronic myelogenous leukemia. Also, she developed graft versus host disease following bone marrow transplantation. Investigations led to the diagnosis of muscle specific kinase antibody related myasthenia gravis. There have been only two case reports of muscle specific kinase antibody positive myasthenia gravis after bone marrow transplantation in the literature, but none of the previously reported cases had graft versus host disease.
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