Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Multiple Sclerosis l: Introduction01:19

Multiple Sclerosis l: Introduction

20
Multiple sclerosis is a chronic autoimmune disease of the central nervous system (CNS) that affects the brain, spinal cord, and optic nerves. It is an inflammatory demyelinating disorder and a leading cause of neurological disability in young adults.EpidemiologyMS commonly begins between 20 and 40 years of age and is twice as common in women. Its exact cause remains unclear, but genetic susceptibility contributes, with higher risk in first-degree relatives and identical twins. A greater...
20
Alterations in Muscle Tone ll01:12

Alterations in Muscle Tone ll

27
Alterations in muscle tone are common manifestations of neurological disorders and reflect dysfunction within different nervous system regions. Spasticity, paratonia, and dystonia represent distinct forms of hypertonia, each with unique mechanisms, clinical features, and diagnostic importance.CharacteristicsSpasticity happens from upper motor neuron lesions and is characterized by velocity-dependent resistance to passive movement. Clinical features include:Exaggerated deep tendon reflexesClonus...
27
Alterations in Muscle Tone lll01:11

Alterations in Muscle Tone lll

29
Rigidity and myotonia are distinct abnormalities of muscle tone that affect resistance and relaxation during movement. Although both involve altered muscle contraction, they arise from different neurological and muscular mechanisms.CharacteristicsRigidity is characterized by uniform resistance to passive movement across the entire range, independent of speed, affecting flexors and extensors equally. It may appear as lead-pipe rigidity (smooth, constant resistance) or cogwheel rigidity...
29
Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

2.2K
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
2.2K
Parkinson Disease ll: Pathophysiology01:24

Parkinson Disease ll: Pathophysiology

28
Parkinson disease (PD) is a progressive neurodegenerative disorder primarily affecting movement, with additional non-motor features. Its pathophysiology involves complex interactions among genetic susceptibility, environmental exposures, and cellular dysfunction, including dopaminergic neuron loss, protein aggregation, and mitochondrial impairment.Selective NeurodegenerationA key feature is the degeneration of dopaminergic neurons in the substantia nigra pars compacta, leading to reduced...
28
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

2.2K
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
2.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Heterogenous Neuropathology in a Pedigree with RAB39B-Related Parkinson's Disease.

Movement disorders : official journal of the Movement Disorder Society·2026
Same author

Correction: The Natural History Study and Biomarker Collection of the Clinical Research Consortium for the Study of Cerebellar Ataxia (CRC-SCA).

Cerebellum (London, England)·2025
Same author

Microvascular Decompression in a Patient With Positional Hemifacial Spasm: Case Report.

Neurosurgery practice·2025
Same author

The Natural History Study and Biomarker Collection of the Clinical Research Consortium for the Study of Cerebellar Ataxia (CRC-SCA).

Cerebellum (London, England)·2025
Same author

Suicidal Ideation in Spinocerebellar Ataxia.

The Journal of neuropsychiatry and clinical neurosciences·2025
Same author

Spinocerebellar Ataxia Progression Measured with the Patient-Reported Outcome Measure of Ataxia.

Movement disorders : official journal of the Movement Disorder Society·2025
Same journal

Preface.

Physical medicine and rehabilitation clinics of North America·2026
Same journal

Pain Unbound: A Comprehensive Review.

Physical medicine and rehabilitation clinics of North America·2026
Same journal

Dual Frontiers Cancer and Palliative Care.

Physical medicine and rehabilitation clinics of North America·2026
Same journal

Pain Management Across Special Populations: Pediatrics, Geriatrics, and Pregnancy.

Physical medicine and rehabilitation clinics of North America·2026
Same journal

Healing from Within: Regenerative Medicine in Pain Therapy.

Physical medicine and rehabilitation clinics of North America·2026
Same journal

The Brain in Pain: Exploring Central Pain Disorders.

Physical medicine and rehabilitation clinics of North America·2026
See all related articles

Related Experiment Video

Updated: May 5, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

12.4K

Movement disorders in multiple sclerosis.

Patricia K Oakes1, Sindhu R Srivatsal, Marie Y Davis

  • 1Department of Neurology, University of Washington, Seattle, WA, USA.

Physical Medicine and Rehabilitation Clinics of North America
|December 10, 2013
PubMed
Summary
This summary is machine-generated.

This review covers movement disorders, which involve abnormal movements like tremors and parkinsonism. It explores their classification, occurrence in multiple sclerosis, and treatment strategies.

Keywords:
AtaxiaMovement disorderMultiple sclerosisRestless legsTremor

More Related Videos

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
08:51

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

9.7K
Sagittal Plane Kinematic Gait Analysis in C57BL/6 Mice Subjected to MOG35-55 Induced Experimental Autoimmune Encephalomyelitis
13:02

Sagittal Plane Kinematic Gait Analysis in C57BL/6 Mice Subjected to MOG35-55 Induced Experimental Autoimmune Encephalomyelitis

Published on: November 4, 2017

8.1K

Related Experiment Videos

Last Updated: May 5, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

12.4K
Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
08:51

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla

Published on: February 19, 2021

9.7K
Sagittal Plane Kinematic Gait Analysis in C57BL/6 Mice Subjected to MOG35-55 Induced Experimental Autoimmune Encephalomyelitis
13:02

Sagittal Plane Kinematic Gait Analysis in C57BL/6 Mice Subjected to MOG35-55 Induced Experimental Autoimmune Encephalomyelitis

Published on: November 4, 2017

8.1K

Area of Science:

  • Neurology
  • Movement Disorders

Background:

  • Movement disorders encompass conditions with hypokinetic, hyperkinetic, or uncoordinated movements.
  • These include tremors, dystonia, parkinsonism, chorea, tics, and ataxia.
  • The classification is based on phenomenology, specific syndromes, or underlying etiology.

Purpose of the Study:

  • To review the terminology used in describing movement disorders.
  • To discuss specific movement disorders and their manifestation in multiple sclerosis.
  • To provide an overview of current treatment options for movement disorders.

Main Methods:

  • Literature review of movement disorder terminology.
  • Analysis of movement disorders in the context of multiple sclerosis.
  • Synthesis of information on treatment modalities.

Main Results:

  • Established terminology for describing abnormal movements.
  • Detailed the presentation of various movement disorders in multiple sclerosis patients.
  • Summarized available therapeutic interventions.

Conclusions:

  • Understanding movement disorder terminology is crucial for accurate diagnosis and communication.
  • Movement disorders are a significant clinical feature in multiple sclerosis, impacting patient care.
  • A comprehensive approach to treatment is necessary for managing these complex conditions.