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Related Concept Videos

Allergic Reactions02:06

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Overview
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Allergic Reactions: Anaphylaxis01:30

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Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
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Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
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Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
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Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial...
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Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
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Related Experiment Video

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A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
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[Cypress pollen allergy].

D Charpin1, M Calleja, C Pichot

  • 1Inserm UMR 600, CNRS UMR 6212, service de pneumologie-allergologie, clinique des bronches, allergie et sommeil, Aix-Marseille université, chemin des Bourrelly, 13015 Marseille, France.

Revue Des Maladies Respiratoires
|December 10, 2013
PubMed
Summary
This summary is machine-generated.

Cypress pollen is a significant allergen, causing widespread allergic rhinitis and conjunctivitis, especially in Mediterranean regions. Rising global temperatures are increasing cypress allergy prevalence and extending pollination seasons.

Keywords:
AllergieAllergyCypressCyprèsHealthPollenPollinosesPollinosisSanté

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Area of Science:

  • Botany and Allergy Research
  • Focuses on the Cupressaceae family, including various cypress and juniper species.
  • Highlights the prevalence and impact of cypress pollen as an allergen.

Context:

  • Cupressaceae family, encompassing 140 species, is a major source of allergenic pollen.
  • Pollination periods of key species like Cupressus sempervirens and Cupressus arizonica are extended by global warming.
  • Cypress pollen is the primary pollinator in Mediterranean countries, contributing to half of the total pollen load.

Purpose:

  • To review the significance of cypress pollen as an allergen.
  • To discuss the prevalence, risk factors, and clinical manifestations of cypress allergy.
  • To explore treatment and avoidance strategies for cypress allergy.

Summary:

  • Cypress pollen allergy affects 5-13% of the general population and 9-35% of allergy clinic outpatients.
  • Major allergens are group 1, with high cross-reactivity among Cupressaceae species.
  • Risk factors include genetics, pollen exposure, and potentially air pollutants.
  • A distinct subgroup of non-atopic individuals develops cypress allergy, characterized by later onset and monosensitization.

Impact:

  • Cypress allergy prevalence is increasing, with a threefold rise observed in some studies.
  • Allergic rhinitis and conjunctivitis are the main clinical symptoms.
  • Cross-reactivity with peach allergy is noted.
  • Treatment options include avoidance and hyposensitization (sublingual route preferred).
  • Community-level avoidance strategies involve using alternative plants or low-pollinating cypress varieties.