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Related Concept Videos

Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

827
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
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Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

926
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
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Related Experiment Video

Updated: May 5, 2026

Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
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Liver transplantation using low-weight recipients from a graft split program.

C San Miguel1, Y Fundora, K Muffak

  • 1Virgen de las Nieves University Hospital, Granada, Spain.

Transplantation Proceedings
|December 10, 2013
PubMed
Summary
This summary is machine-generated.

Split liver transplantation using partial grafts from deceased donors is a viable option to increase organ availability. This technique showed promising results, with 75% of recipients surviving and no major complications reported.

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Area of Science:

  • Hepatology
  • Transplantation Surgery
  • Organ Donation

Background:

  • Liver transplantation (LT) faces challenges due to donor organ shortages.
  • Split liver (SL) techniques offer a potential solution by utilizing partial grafts.
  • Collaborative programs between institutions can optimize organ utilization.

Purpose of the Study:

  • To evaluate the experience and outcomes of split liver transplantation using partial grafts from deceased donors.
  • To assess the feasibility and safety of a shared SL program between two hospitals.
  • To determine the impact of SL transplantation on recipient survival and complications.

Main Methods:

  • Observational, retrospective study of patients undergoing SL transplantation between January 2006 and December 2012.
  • Analysis of clinical data from both donors and recipients.
  • Surgical technique involved temporary portocaval shunt, hepatic vein confluence to donor vena cava anastomosis, arterial anastomosis, and hepato-choledochal reconstruction.

Main Results:

  • Four patients (2% of total LT) received SL grafts.
  • Causes of LT included alcoholic cirrhosis (2), cryptogenic cirrhosis, and primary biliary cirrhosis (PBC).
  • No cases of postreperfusion syndrome or vascular thrombosis were observed; no retransplantation was needed. Three out of four patients (75%) are currently alive, with one death due to mesenteric ischemia.

Conclusions:

  • Split liver transplantation using partial grafts from deceased donors is a safe and effective strategy.
  • Collaborative SL programs can expand donor pool and address organ scarcity.
  • The technique demonstrated favorable outcomes, including high survival rates and absence of major vascular complications.