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Updated: May 5, 2026

Recapitulating Suckling-to-Weaning Transition In Vitro using Fetal Intestinal Organoids
Published on: November 15, 2019
The young and the Wnt-less: transplantable fetal intestinal spheroids without Wnts
Hiroyuki Miyoshi1, Thaddeus S Stappenbeck
1Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.
Abstract:
The differences between fetal and adult intestinal stem cells are unclear, and understanding this relationship could present novel therapeutic opportunities. Fordham et al. (2013) and Mustata et al. (2013) report a potential source of transplantable epithelial cells from fetal gut that can convert into adult intestinal stem and differentiated cells.
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