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Updated: May 5, 2026

Convergent Polishing: A Simple, Rapid, Full Aperture Polishing Process of High Quality Optical Flats & Spheres
Published on: December 1, 2014
Refining a Jagged edge
1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 45 Shattuck Street, Boston, MA 02115, USA; Department of Cancer Biology, Dana Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA; Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.
Abstract:
In a recent Cell Reports article, Chillakuri and colleagues showed that the N-terminal "MNNL" domain of the essential Notch ligand Jagged1 resembles a C2 domain and relies on calcium binding to facilitate productive signal transduction.
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