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Updated: May 5, 2026
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Published on: September 5, 2011
Perinatal- and procedure-related outcomes following radiofrequency ablation in monochorionic pregnancy
Sailesh Kumar1, Gowrishankar Paramasivam2, Eko Zhang2
1Centre for Fetal Care, Queen Charlotte's and Chelsea Hospital, Imperial College London, London, England, United Kingdom; Institute for Reproductive and Developmental Biology, Imperial College London, London, England, United Kingdom; Mater Research Institute, University of Queensland, Brisbane, Queensland, Australia.
Objective:
We sought to assess the efficacy, complication rates, and outcomes for complex monochorionic pregnancies undergoing selective fetal reduction using radiofrequency ablation (RFA).
Study Design:
In this prospective observational study, 100 consecutive cases of selective fetal reduction using RFA were analyzed. All cases were managed at the Centre for Fetal Care at Queen Charlotte's and Chelsea Hospital in London. Indications for offering RFA, details of the procedure, and pregnancy outcomes were collected and analyzed.
Results:
The main indications for RFA were discordant fetal anomaly and twin-twin transfusion syndrome. Overall live birth rate was 78% and the median gestation at delivery was 35.15 weeks. Delivery <32 weeks' gestation occurred in 17.9% of cases. Postprocedure abnormal antenatal magnetic resonance imaging occurred in 3% of cases. There was no statistical difference in outcomes with regard to gestation when the procedure was performed or the indication for the RFA.
Conclusion:
RFA appears to be a reasonable option for selective fetal reduction in complex monochorionic pregnancies with an overall survival rate of 78%.
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