Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Divergent modes of episodic organization underlie whether emotional learning enhances memory across event boundaries.

Psychonomic bulletin & review·2026
Same author

Stress disrupts hippocampal integration of overlapping events and memory inference in humans.

Science advances·2026
Same author

Multi-session CBM-I for social anxiety: examining psychopathology, cognitive, neural, and psychophysiological effects in a randomized controlled trial.

Translational psychiatry·2026
Same author

The effects of rumination and reappraisal on repeated exposure to stress.

Comprehensive psychoneuroendocrinology·2026
Same author

Approach-avoidance tendencies in problematic usage of the internet: Evidence from a multisite study.

Journal of behavioral addictions·2026
Same author

Timing Matters: Providing Contingency Instructions to Modify Fear Extinction Memories in Anxiety Disorders.

Biological psychiatry. Cognitive neuroscience and neuroimaging·2026

Related Experiment Video

Updated: May 5, 2026

Place and Response Learning in the Open-field Tower Maze
08:31

Place and Response Learning in the Open-field Tower Maze

Published on: October 28, 2015

9.9K

Sex differences in stress effects on response and spatial memory formation.

Friederike M Guenzel1, Oliver T Wolf1, Lars Schwabe2

  • 1Institute of Cognitive Neuroscience, Department of Cognitive Psychology, Ruhr-University Bochum, Universitaetsstrasse 150, 44780 Bochum, Germany; International Graduate School of Neuroscience (IGSN), Ruhr-University Bochum, Universitaetsstrasse 150, 44801 Bochum, Germany.

Neurobiology of Learning and Memory
|December 10, 2013
PubMed
Summary

Acute stress impacts learning and memory differently based on sex. Stress impaired stimulus-response (S-R) memory in men, while impairing spatial memory in women.

Keywords:
GlucocorticoidsHippocampusResponse learningSpatial learningStressStriatum

More Related Videos

An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze
14:24

An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze

Published on: July 29, 2025

1.8K
Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm
07:26

Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm

Published on: May 4, 2020

3.0K

Related Experiment Videos

Last Updated: May 5, 2026

Place and Response Learning in the Open-field Tower Maze
08:31

Place and Response Learning in the Open-field Tower Maze

Published on: October 28, 2015

9.9K
An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze
14:24

An Appetitive Spatial Working Memory Task for Mice in a Semi-Automated 8-Arm Radial Maze, Reducing Fearful Memory Association in the Maze

Published on: July 29, 2025

1.8K
Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm
07:26

Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm

Published on: May 4, 2020

3.0K

Area of Science:

  • Neuroscience
  • Psychology

Background:

  • Stress hormones are known to influence learning and memory.
  • While effects on hippocampus-dependent memory are documented, stress impact on striatum-dependent stimulus-response (S-R) learning is less understood.
  • Previous research suggests stress hormones can enhance S-R memory consolidation but impair retrieval.

Purpose of the Study:

  • To investigate the effects of acute stress on stimulus-response (S-R) memory acquisition in humans.
  • To compare stress effects on S-R memory with those on hippocampus-dependent spatial memory.
  • To explore the role of sex in stress-induced memory alterations.

Main Methods:

  • Healthy men and women were exposed to an acute stressor (socially evaluated cold pressor test, SECPT) or a control condition.
  • Participants completed a stimulus-response (S-R) task and two spatial learning tasks.
  • Memory performance was assessed one week after the tasks.

Main Results:

  • Stress impaired S-R memory performance in men but not in women.
  • Conversely, stress impaired spatial memory in women but not in men.
  • Sex differences were observed in the impact of stress on different memory systems.

Conclusions:

  • Stress can affect learning and memory processes beyond the hippocampus.
  • Sex plays a critical role in how stress influences various memory systems.
  • These findings highlight the complex interplay between stress, sex, and memory consolidation.