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Aldehyde dehydrogenase 3A1 protects airway epithelial cells from cigarette smoke-induced DNA damage and cytotoxicity

Jun-Ho Jang1, Shannon Bruse2, Yushi Liu2

  • 1Division of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, University of New Mexico, Albuquerque, NM 87131, USA; New Mexico VA Health Care System, Albuquerque, NM 87108, USA; COPD Program, Lovelace Respiratory Research Institute, Albuquerque, NM 87108, USA.

Free Radical Biology & Medicine
|December 10, 2013
PubMed

Keywords:
ALDH3A1Airway epithelial cellsChronic obstructive pulmonary diseaseCigarette smokeCytotoxicityDNA damageFANCD2Free radicalsReactive aldehydes

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