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Related Concept Videos

Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

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DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
558

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Imaging small vessel-associated white matter changes in aging.

D H Salat1

  • 1Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Department of Radiology, Charlestown, MA, USA; Neuroimaging Research for Veterans Center, Boston VA Healthcare System, Boston, MA, USA.

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|December 10, 2013
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Summary

Cerebrovascular changes, even subtle ones affecting small vessels in the brain, are linked to age-related cognitive and neurological decline. These vascular alterations can impact overall functional status later in life.

Keywords:
agingcerebral blood flowcerebrovascularhyperintensitiesmicrovascularwhite matter

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Area of Science:

  • Neuroscience
  • Gerontology
  • Vascular Biology

Background:

  • Age-associated cognitive, psychiatric, and neurological conditions are common in older adults.
  • Cerebrovascular structure and function alterations are implicated in these conditions.
  • Small vessel damage in the brain may mediate detrimental age-associated effects.

Purpose of the Study:

  • To review the relationship between aging, cerebrovascular health, and neural health.
  • To highlight the impact of vascular changes on functional status in late life.

Main Methods:

  • Review of existing scientific literature.
  • Synthesis of research demonstrating links between vascular and neural health over the lifespan.

Main Results:

  • Advancing age is associated with changes in both vascular and neural health.
  • Subtle small vessel damage in the brain can impact cognitive and neurological function.
  • Vascular changes, even in individuals with low-to-moderate risk, can affect late-life functional status.

Conclusions:

  • Cerebrovascular health is critical for maintaining cognitive and neurological function throughout aging.
  • Early-life and ongoing vascular changes can have long-term consequences for brain health.
  • Further research is needed to fully understand and mitigate age-related cerebrovascular damage.