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[Serum trace elements and myocardial infarction].

L Dumolard, J Arnaud, B Veyrat

    Annales De Biologie Clinique
    |January 1, 1986
    PubMed
    Summary
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    Serum zinc, nickel, and copper levels change during myocardial infarction (MI). Zinc decreases initially, while nickel and copper increase, with levels returning to normal over time. These trace element shifts offer insights into heart attack pathophysiology.

    Area of Science:

    • Biochemistry
    • Cardiology
    • Trace Element Analysis

    Context:

    • Myocardial infarction (MI) is a critical cardiovascular event.
    • Trace elements play vital roles in physiological processes.
    • Understanding metabolic changes during MI is crucial for diagnosis and treatment.

    Purpose:

    • To review and synthesize published data on trace element concentrations during myocardial infarction.
    • To analyze the dynamic changes in serum zinc, nickel, and copper levels post-MI.
    • To explore potential explanations for observed trace element disturbances.

    Summary:

    • Serum zinc concentrations decrease within the first two days following acute myocardial infarction, normalizing within two weeks.
    • Serum nickel levels show an increase during the initial 36 hours post-MI.

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  • Serum copper concentrations rise during the first four days after myocardial infarction, with explanations for these fluctuations discussed.

    • Impact:

    • Provides a consolidated overview of trace element alterations in acute myocardial infarction.
    • Highlights potential biomarkers for MI diagnosis and monitoring.
    • Contributes to a deeper understanding of the biochemical response to cardiac injury.