Related Experiment Video
Updated: May 5, 2026

Genetic Analysis of Hereditary Transthyretin Ala97Ser Related Amyloidosis
Published on: June 9, 2018
[Correlation between ABCC11 gene single nucleotide polymorphism and the incidence of axillary osmidrosis in Chinese
Yang Sun1, Jianhong Long, Yongjie Wang
1Department of Plastics and Cosmetic Surgery, Xiangya Hospital, Central South University, Changsha 410008, China.
Objective:
To explore the relationship between ABCC11 gene single nucleotide polymorphism (SNP) and the incidence of axillary osmidrosis in Chinese Han population.
Methods:
The genotype of ABCC11 gene SNP at rs17822931 in 40 patients with axillary osmidrosis and 5 normal Han people was detected and analyzed by high resolution melt and gene sequencing.
Results:
The detection of the genotype of ABCC11 gene SNP at rs17822931 showed that: 37 of the 40 patients were GA genotype and the other 3 were GG genotype, while the 5 normal subjects were AA genotype.
Conclusion:
SNP in ABCC11 is the genetic cause of axillary osmidrosis. GG or GA leads to axillary osmidrosis, while AA allele presents the absence of axillary osmidrosis.
Related Concept Videos
Single Nucleotide Polymorphisms-SNPs
Genome-wide Association Studies-GWAS
GWAS does not require the identification of the target gene involved in...
Pharmacogenetics of Drug Transporters: P-Glycoprotein and Solute Carrier Transporters
Pleiotropy
