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In vivo induction of Ia antigens on rat keratinocytes by gamma-interferon

A Scheynius, C Johansson, P H van der Meide

    The British Journal of Dermatology
    |November 1, 1986
    PubMed

    Recombinant rat IFN-gamma was found to induce Ia antigen expression on rat keratinocytes in vivo. Strong expression of Ia antigen on keratinocytes of rat ears was produced after intradermal injections of 10,000 U IFN-gamma once daily on 3 successive days. The expression was still pronounced 2 days after the last injection, but had disappeared 4 days later.

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