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Granulocytic sarcoma of the prostate. Two cases causing urinary obstruction
Cancer
|January 1, 1987
Summary
Prostatic granulocytic sarcoma can cause urinary obstruction in patients with myelodysplastic syndromes or acute myeloblastic leukemia. This rare condition should be considered in the differential diagnosis for urinary issues in these patients.
Area of Science:
- Oncology
- Hematology
- Urology
Background:
- Granulocytic sarcoma is a rare extramedullary tumor composed of immature granulocytes.
- It can occur in patients with myeloproliferative or myelodysplastic syndromes.
- Urinary obstruction is an uncommon but serious presentation.
Observation:
- Two cases of prostatic granulocytic sarcoma presenting with urinary obstruction are described.
- Diagnosis was confirmed via tissue examination using hematoxylin and eosin and specific esterase stains.
- The prostatic involvement was unexpected in both patients.
Findings:
- One patient had myelodysplastic syndrome.
- The other patient had acute myeloblastic leukemia.
- Prostatic granulocytic sarcoma was the cause of urinary obstruction in both instances.
Implications:
- Granulocytic sarcoma should be included in the differential diagnosis of urinary obstruction in patients with myeloproliferative or myelodysplastic syndromes.
- Early recognition and diagnosis are crucial for appropriate management.
- This highlights the diverse clinical manifestations of granulocytic sarcoma.