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Freiberg's infraction: diagnosis and treatment
Paul G Talusan1, Pablo J Diaz-Collado, John S Reach
1Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, Connecticut.
Freiberg's infraction is a rare bone condition affecting lesser metatarsal heads, primarily in adolescent females. While the cause is unknown, treatments aim to reduce pressure, and outcomes are generally good.
Area of Science:
- Orthopedics
- Podiatry
- Radiology
Background:
- Freiberg's infraction involves cartilage degeneration of metatarsal heads.
- Adolescent females are typical patients, but it can affect any age or sex.
- The second and third metatarsals are most commonly affected.
Purpose of the Study:
- To review the pathophysiology, diagnosis, and management of Freiberg's infraction.
- To highlight diagnostic imaging findings.
- To discuss treatment outcomes.
Main Methods:
- Clinical diagnosis supported by imaging (radiographs, bone scans, MRI).
- Review of nonoperative (pressure reduction, unloading) and operative (osteotomies, transplants, arthroplasty) treatments.
- Discussion of disease progression and healing potential.
Main Results:
- Early diagnosis can be challenging with normal radiographs.
- Imaging reveals characteristic changes as the condition progresses.
- Both nonoperative and operative treatments yield good to excellent patient outcomes, allowing return to activity.
Conclusions:
- The exact pathophysiology of Freiberg's infraction remains unclear.
- Early intervention and appropriate management are key to successful outcomes.
- Further research is needed for prevention strategies.
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