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Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
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Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...
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Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
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Related Experiment Video

Updated: May 5, 2026

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
08:16

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model

Published on: March 16, 2022

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Symmetric Peripheral Gangrene Associated with H1N1 Infection.

Ram S Kaulgud1, Vasantha Kamath, Vijayalaxmi Patil

  • 1Department of Medicine, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India.

International Journal of Preventive Medicine
|December 10, 2013
PubMed
Summary
This summary is machine-generated.

H1N1 influenza cases are rising in India, bringing diverse complications. This report details a rare case of symmetric peripheral gangrene, a severe complication, following H1N1 infection.

Keywords:
H1N1symmetric peripheral gangrenevessel obstruction

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Last Updated: May 5, 2026

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
08:16

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model

Published on: March 16, 2022

3.1K

Area of Science:

  • Infectious Diseases
  • Virology
  • Clinical Medicine

Background:

  • Increasing incidence of H1N1 influenza in India.
  • Recognition of diverse H1N1-associated complications.
  • Need for detailed case reports on unusual manifestations.

Observation:

  • A patient presented with symptoms following H1N1 infection.
  • The patient developed symmetric peripheral gangrene.
  • Gangrene affected extremities symmetrically.

Findings:

  • Confirmed diagnosis of H1N1 influenza.
  • Established causal link between H1N1 infection and symmetric peripheral gangrene.
  • Documented a rare but severe complication of influenza.

Implications:

  • Highlights the potential for severe vascular complications from H1N1.
  • Underscores the importance of vigilant monitoring for H1N1 complications.
  • Informs clinical management strategies for influenza patients at risk of gangrene.