Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neuroplasticity01:01

Neuroplasticity

2.6K
Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.
2.6K
Plasticity00:58

Plasticity

2.2K
Plasticity is the property where an object loses its elasticity and undergoes irreversible deformation, even after the deformation forces are eliminated. If a material deforms irreversibly without increasing stress or load, then this is called ideal plasticity. For example, when a force is applied to an aluminum rod, it changes its shape, but it does not return to its original shape once the force is removed. Plastic deformation or ductility is thus a permanent deformation or change in the...
2.2K
Cognitive Learning01:21

Cognitive Learning

1.6K
Cognitive learning is based on purposive behavior, incidental learning, and insight learning.
E. C. Tolman's theory of purposive behavior emphasizes that much behavior is goal-directed. He argued that to understand behavior, we must look at the entire sequence of actions leading to a goal. For instance, high school students study hard, not just due to past reinforcement but also to achieve the goal of getting into a good college.
Tolman introduced the idea that behavior is influenced by...
1.6K
Long-term Potentiation01:25

Long-term Potentiation

2.7K
Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
Hebbian LTP
LTP can occur when...
2.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Disability, anti-disability, post-disability: A critical trajectory.

Developmental medicine and child neurology·2026
Same author

Polarity-dependent modulation of sensory circuits by cerebellar tDCS: local and distant effects.

Scientific reports·2026
Same author

What is the impact of childhood-onset disability research - and what should it be?

Developmental medicine and child neurology·2026
Same author

Descripción actualizada de la parálisis cerebral.

Developmental medicine and child neurology·2026
Same author

Foreword.

Developmental medicine and child neurology·2026
Same author

Description actualisée de la paralysie cérébrale.

Developmental medicine and child neurology·2026

Related Experiment Video

Updated: May 5, 2026

Assessment of Long-term Depression Induction in Adult Cerebellar Slices
09:30

Assessment of Long-term Depression Induction in Adult Cerebellar Slices

Published on: October 16, 2019

6.2K

Translational approach to behavioral learning: lessons from cerebellar plasticity.

Guy Cheron1, Bernard Dan, Javier Márquez-Ruiz

  • 1Laboratory of Electrophysiology, Université de Mons, 7000 Mons, Belgium ; Laboratory of Neurophysiology and Movement Biomechanics, CP640, ULB Neuroscience Institut, Université Libre de Bruxelles, 1070 Brussels, Belgium.

Neural Plasticity
|December 10, 2013
PubMed
Summary

The cerebellum

More Related Videos

Slice Patch Clamp Technique for Analyzing Learning-Induced Plasticity
11:56

Slice Patch Clamp Technique for Analyzing Learning-Induced Plasticity

Published on: November 11, 2017

18.3K
Author Spotlight: Unveiling Neural Mechanisms Through Automated Evaluation of Motor Learning and Myelin Plasticity Studies Using the Erasmus Ladder
08:51

Author Spotlight: Unveiling Neural Mechanisms Through Automated Evaluation of Motor Learning and Myelin Plasticity Studies Using the Erasmus Ladder

Published on: December 15, 2023

2.2K

Related Experiment Videos

Last Updated: May 5, 2026

Assessment of Long-term Depression Induction in Adult Cerebellar Slices
09:30

Assessment of Long-term Depression Induction in Adult Cerebellar Slices

Published on: October 16, 2019

6.2K
Slice Patch Clamp Technique for Analyzing Learning-Induced Plasticity
11:56

Slice Patch Clamp Technique for Analyzing Learning-Induced Plasticity

Published on: November 11, 2017

18.3K
Author Spotlight: Unveiling Neural Mechanisms Through Automated Evaluation of Motor Learning and Myelin Plasticity Studies Using the Erasmus Ladder
08:51

Author Spotlight: Unveiling Neural Mechanisms Through Automated Evaluation of Motor Learning and Myelin Plasticity Studies Using the Erasmus Ladder

Published on: December 15, 2023

2.2K

Area of Science:

  • Neuroscience
  • Behavioral Neuroscience
  • Cellular Neuroscience

Background:

  • Cerebellar plasticity is crucial for learning.
  • The cerebellum's connections with the inferior olive and basal ganglia support various behaviors.
  • Purkinje cells, regulated by climbing fibers, are key to cerebellar learning.

Purpose of the Study:

  • To review cerebellar functions in behavioral learning.
  • To integrate evidence of neuronal plasticity into a translational perspective.
  • To examine the causal links between neural circuits, signals, and plasticity.

Main Methods:

  • Focus on behaving or alert animal physiology.
  • Analysis of three experimental paradigms: vestibulo-ocular reflex/smooth pursuit, eyeblink conditioning, and sensory envelope plasticity.
  • Utilizing neural unit and local field potential recordings.

Main Results:

  • Demonstrated spike-timing-dependent plasticity in the cerebellum.
  • Highlighted the cerebellum's strategic role in processing plasticity mechanisms.
  • Linked cerebellar circuits to specific behavioral learning processes.

Conclusions:

  • The cerebellum is central to understanding fundamental and translational mechanisms of learning.
  • Spike-timing-dependent plasticity is a key mechanism.
  • Cerebellar networks integrate cellular and network-level plasticity for behavior.