[Sero-epidemiological analysis for entervirus 71 infection of adults in Beijing]
Jing-Jing Wang1, Wei Wu, Hui-Jie Pan
1Beijiing Hospital, Beijing 100730, China. dongich@cmde.org.cn
Objective:
To evaluate the enterovirus 71 (EV 71) protective antibody level of health adults people in Beijing.
Methods:
Serum samples and information of participants were collected from hospitals in Beijing. EV71 IgG was tested by enzyme-linked immunoadsordent assay (ELISA). EV 71 neutralization antibody was evaluated by micro-cytopathic effect neutralization test (MCPENT).
Results:
486 participants were enrolled. Age range was 19-62 years old. The average EV 71 IgG positive rate was 40. 3% , there are no significant difference between the EV 71 IgG positive rate of male and female. The rate of EV 71 neutralization antibody which title high than 1:256 is 13.3%. The rate of EV 71 IgG and the titile of EV 71 neutralization antibody are decreasing by the age.
Conclusion:
40% of health adults of Beijing area have EV71 protective antibody. But the title higher than 1:256 is only 13.3%. EV 71 protective antibody decreases significantly with the age.
