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Chromogenic In Situ Hybridization as a Tool for HPV-Related Head and Neck Cancer Diagnosis
Published on: June 14, 2019
Association between oral DNA-HPV and genital DNA-HPV
Lisandra Rocha Vidotti1, Flávia Castello Branco Vidal, Sally Cristina Moutinho Monteiro
1Post-Graduation Program for Maternal Child Health, Federal University of Maranhão (UFMA), São Luis, Brazil.
Background:
Human papillomavirus (HPV) infection is one of the most common sexually transmitted diseases worldwide and is observed in both men and women. The presence of the virus is often associated with benign and malignant neoplasms of the oral cavity. We wished to investigate whether HPV infection in the genitalia was associated with HPV infection in the oral mucosa.
Methods:
The prevalence of HPV in the oral cavity and genitalia was evaluated by DNA extraction from genital and oral cavity samples of 105 women, followed by nested PCR.
Results And Conclusions:
The prevalence of HPV in the oral cavity was significantly higher in women who had genital HPV (P < 0.0001). Oral sex, alcohol, and tobacco consumption were not associated with the oral HPV infection.
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