MRI and FDG PET/CT findings in 3 cases of spinal infectious arachnoiditis

Aisheng Dong1, Changjing Zuo, Ping Zhang

  • 1From the Departments of *Nuclear Medicine, †Neurology, ‡Radiology, and §Orthopedic Surgery, Changhai Hospital, Second Military Medical University, Shanghai, China.

Clinical Nuclear Medicine
|December 11, 2013
PubMed

Insights

Spinal arachnoiditis, an inflammation of the spinal cord

Area of Science:

  • Neurology
  • Radiology
  • Infectious Diseases

Background:

  • Spinal arachnoiditis involves inflammation and scarring of the spinal cord's arachnoid membrane.
  • Diagnosis often relies on MRI, but FDG PET/CT findings are infrequently documented.

Observation:

  • Three cases of infectious spinal arachnoiditis (1 pyogenic, 2 tuberculous) were analyzed.
  • MRI revealed thickened spinal meninges with significant enhancement.
  • FDG PET/CT in two cases showed intense linear uptake along the spinal canal.

Findings:

  • FDG PET/CT demonstrates characteristic intense linear uptake in infectious spinal arachnoiditis.
  • Combined MRI and FDG PET/CT imaging can pinpoint infection sites.
  • This imaging combination aids in assessing infection activity.

Implications:

  • FDG PET/CT offers valuable insights into spinal arachnoiditis, complementing MRI.
  • Accurate identification and assessment of infection activity are crucial for effective treatment.
  • Further research into FDG PET/CT utility in spinal infections is warranted.

Related Concept Videos

Viral Meningitis01:18

Viral Meningitis

Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
199
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
15
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial...
21