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Updated: May 5, 2026
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Generation and Expansion of Primary, Malignant Pleural Mesothelioma Tumor Lines
Published on: April 21, 2022
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[Primary pulmonary malignant melanoma].
Hiroshi Yabuki1, Toshiharu Tabata, Takafumi Sugawara
1Department of Thoracic Surgery, Tohoku Pharmaceutical University Hospital, Sendai, Japan.
Kyobu Geka. the Japanese Journal of Thoracic Surgery
|December 11, 2013
Summary
This case report details a rare instance of primary pulmonary malignant melanoma in a 63-year-old man, initially misdiagnosed as non-small-cell lung cancer. Surgical resection was successful, highlighting the importance of accurate diagnosis for this uncommon lung cancer.
Area of Science:
- Oncology
- Pulmonology
- Pathology
Background:
- Primary pulmonary malignant melanoma is an extremely rare condition, often presenting diagnostic challenges.
- This case involves a 63-year-old male initially diagnosed with non-small-cell lung cancer based on initial bronchoscopic cytology.
Observation:
- Chest computed tomography (CT) revealed a 60 mm mass in the left lung.
- Video-assisted thoracic surgery (VATS) left pneumonectomy with mediastinal lymph node dissection was performed.
- Pathological examination confirmed neoplastic cells containing melanin, establishing the diagnosis of malignant melanoma.
Findings:
- The pathological stage was pT2bN1M0, Stage IIB, with lymph node metastasis in stations #10, #11, and #12.
- No other lesions were identified, supporting the left lung as the primary site.
- Adjuvant chemotherapy was not administered post-surgery.
Implications:
- Accurate pathological diagnosis is crucial for managing rare pulmonary neoplasms.
- Surgical resection is a primary treatment modality for resectable primary pulmonary malignant melanoma.
- This case contributes to the limited literature on primary pulmonary melanoma, emphasizing diagnostic considerations.
