Do current animal models of intracerebral hemorrhage mirror the human pathology?

Opeolu Adeoye1, Joseph F Clark, Pooja Khatri

  • 1Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA, opeolu.adeoye@uc.edu.

Although intracerebral hemorrhage (ICH) has no proven treatment, well-designed studies using animal models of ICH may lead to the development of novel therapies. We briefly review current animal models of ICH. Furthermore, we discuss how these models may be utilized and targeted to facilitate translation of preclinical findings to the clinical arena.

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