Vignetting and field of view with the KAMRA corneal inlay

To evaluate the effect of the KAMRA corneal inlay on the retinal image brightness in the peripheral visual field.

A KAMRA inlay was "implanted" into a theoretical eye model in a corneal depth of 200 microns. Corneal radius was varied to a steep, normal, and flat (7.37, 7.77, and 8.17 mm) version keeping the proportion of anterior to posterior radius constant. Pupil size was varied from 2.0 to 5.0 mm. Image brightness was determined for field angles from -70° to 70° with and without KAMRA and proportion of light attenuation was recorded.

In our parameter space, the attenuation in brightness ranges in between 0 and 60%. The attenuation in brightness is not affected by corneal shape. For large field angles where the incident ray bundle is passing through the peripheral cornea, brightness is not affected. For combinations of small pupil sizes (2.0 and 2.5 mm) and field angles of 20-40°, up to 60% of light may be blocked with the KAMRA.

For combinations of pupil sizes and field angles, the attenuation of image brightness reaches levels up to 60%. Our theoretical findings have to be clinically validated with detailed investigation of this vignetting effect.