Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

4.0K
The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
First, in...
4.0K
Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

3.3K
The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
3.3K
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

1.5K
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
1.5K
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

2.4K
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
2.4K
Chronic Obstructive Pulmonary Disease-V: Management01:29

Chronic Obstructive Pulmonary Disease-V: Management

3.3K
Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
3.3K
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

1.2K
Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The CYB5R3 T117S Missense Variant is Associated with Attenuated Riociguat Efficacy in Sickle Cell Disease.

Blood·2026
Same author

Effect of Opt-Out HIV Testing for Adolescent Patients on a Pediatric Hospital Medicine Service.

Hospital pediatrics·2026
Same author

Azithromycin for Preschoolers with Wheezing in the Emergency Department.

The New England journal of medicine·2026
Same author

Medically Unnecessary Venipuncture in Autism Spectrum Disorder Behavior Assessments.

Pediatric emergency care·2026
Same author

Interventions to Prevent Post-Discharge Mortality among Children in Sub-Saharan Africa: A Systematic Review.

The American journal of tropical medicine and hygiene·2026
Same author

Clinician Assessment for Acute Chest Syndrome in Febrile Children With Sickle Cell Disease Revisited.

American journal of hematology·2026

Related Experiment Video

Updated: May 5, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
07:24

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy

1.4K

Asthma management in sickle cell disease.

Esteban Gomez1, Claudia R Morris

  • 1Department of Hematology-Oncology, Children's Hospital & Research Center Oakland, Oakland, CA 94609, USA.

Biomed Research International
|December 11, 2013
PubMed
Summary

Asthma is more common in sickle cell disease (SCD) and worsens its complications. Early asthma management in SCD patients is crucial for reducing mortality and preventing severe pulmonary issues.

Area of Science:

  • Hematology
  • Pulmonology
  • Genetics

Background:

  • Asthma is frequently observed in sickle cell disease (SCD) patients, at rates higher than the general population.
  • The etiology of asthma in SCD is debated, with possibilities including genetic, environmental, and SCD-related hemolytic and inflammatory factors.

Purpose of the Study:

  • To highlight the significant association between asthma and sickle cell disease.
  • To emphasize the impact of asthma exacerbations on SCD complications and mortality.
  • To underscore the need for further research into asthma management within the SCD population.

Main Methods:

  • Review of current literature on asthma and sickle cell disease comorbidity.
  • Analysis of the impact of asthma exacerbations on SCD pathophysiology and clinical outcomes.

More Related Videos

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
08:23

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry

Published on: November 5, 2019

11.2K
Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

18.8K

Related Experiment Videos

Last Updated: May 5, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
07:24

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy

1.4K
Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry
08:23

Characterization of Sickling During Controlled Automated Deoxygenation with Oxygen Gradient Ektacytometry

Published on: November 5, 2019

11.2K
Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
05:23

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

18.8K
  • Identification of knowledge gaps in asthma management strategies for SCD patients.
  • Main Results:

    • Asthma exacerbations in SCD patients contribute to hypoxemia, sickling, and increased risk of pain crises, acute chest syndrome, and stroke.
    • Asthma is linked to higher mortality rates in individuals with sickle cell disease.
    • Limited data exists on the optimal management of asthma in the context of SCD.

    Conclusions:

    • Asthma is a critical comorbidity in SCD that exacerbates disease progression and increases mortality risk.
    • Aggressive and early management of asthma in SCD patients is recommended to mitigate pulmonary complications.
    • Further clinical trials and mechanistic studies are essential to guide effective asthma treatment in SCD.