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[Comparison of four diagnostic criteria for idiopathic inflammatory myopathy]
Xiao-Min Cen1, Ya-Fei Cai, Ling Ma
1Department of Rheumatology and Immunology, West China Hospital, Sichuan University, Chengdu 610041, China.
Objective:
To compare the clinical values of four different criteria for diagnosing idiopathic inflammatory myopathy (IIM).
Methods:
The four different criteria published in 1975, 1995, 1997 and 2004 were applied to 94 IIM patients and 98 patients with other myopathies in West China Hospital.
Results:
The sensitivity of the four criteria for diagnosing IIM was 56. 4% (1975), 87. 2% (1995), 61.7 % (1997), and 52. 1% (2004) respectively. The specificity of the four criteria for diagnosing IIM was 78. 6% (1975), 20. 4% (1995), 78. 6% (1997), and 90. 8% (2004) respectively. The Youden index was 35.0% (1975), 7.6% (1995), 40. 3% (1997), and 42.9% (2004), with an odd product of 4. 74 (1975), 1. 75 (1995), 5. 91 (1997) and 10. 77 (2004) respectively. The Kappa value of the four criteria was 0. 351 (1975, P<0.05), 0. 075 (1995, P>0. 05), 0. 404 (1997, P<0.05 ) and 0. 433 (2004, P<0.05), and their area under the ROC curve was 0. 675 (1975, P=0. 00), 0. 538 (1995, P=0.36),0. 701 (1997, P=0.00) and 0. 715 (2004, P=0.00) respectively.
Conclusion:
The 2004 criteria have a better value in diagnosing IIM.
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