The Cochrane Skin Group: a vanguard for developing and promoting evidence-based dermatology
Anand Reddi1, Laura Prescott, Elizabeth Doney
1Department of Dermatology, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA.
Journal of Evidence-Based Medicine
|December 12, 2013
Summary
The Cochrane Skin Group (CSG) provides high-quality, evidence-based summaries for skin disease prevention, diagnosis, and treatment. Their reviews significantly impact clinical practice guidelines and drive new dermatological research.
Area of Science:
- Dermatology
- Evidence-based medicine
- Systematic reviews
Background:
- The Cochrane Skin Group (CSG) is part of the international Cochrane Collaboration.
- CSG focuses on preparing, maintaining, and disseminating high-quality evidence-based summaries for skin diseases.
- This work supports the prevention, diagnosis, and treatment of dermatological conditions.
Purpose of the Study:
- To present a synopsis of the history, scope, and priorities of the CSG.
- To report outcomes of CSG reviews.
- To critically assess the clinical value of CSG reviews.
Main Methods:
- A descriptive analysis of systematic reviews published by the CSG since its inception.
- Evaluation of review output, impact factor, methodological studies, and influence on clinical guidelines.
- Assessment of patient and public engagement and the triggering of new primary research.
Main Results:
- Since 1997, CSG has published 61 reviews, 34 protocols, and 31 registered titles.
- Reviews cover 1000 skin diseases, with 80% focusing on the top ten diagnoses.
- 40% of reviews offer clear clinical guidance; impact factor was 6.1 in 2011, comparable to top dermatology journals.
Conclusions:
- The CSG is a leader in evidence-based dermatology, fostering a community focused on applying evidence to patient care.
- CSG reviews are high-impact, clinically relevant, and have influenced international dermatology guidelines and research.
- Reviews have identified evidence gaps, stimulating further primary research in dermatology.
Related Concept Videos
Changes in Skin Color: Clinical Perspectives
3.6K
The first thing a clinician sees is the skin, so the examination of the skin should be part of any thorough physical examination. Most skin disorders are relatively benign, but a few, including melanomas, can be fatal if untreated. A couple of the more noticeable disorders, albinism and vitiligo, affect the appearance of the skin and its accessory organs.
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
3.6K
Skin Diseases and Disorders
5.4K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.4K
Role of Skin in Vitamin D Synthesis
8.1K
The skin plays a crucial role in the synthesis of vitamin D, a vital nutrient for various physiological processes in the body. Vitamin D is unique because it can be synthesized in the skin through a series of chemical reactions triggered by exposure to ultraviolet B (UVB) radiation from sunlight.
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
The solar UV B rays (290-315 nm) are absorbed by the skin, and 7-dehydrocholesterol (provitamin D3) photolyzes it to previtamin D3, which undergoes a rapid transformation to vitamin...
8.1K
Skin Cancer
5.2K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
5.2K
Introduction to the Integumentary System
17.4K
The integumentary system is the organ system that comprises the skin and its associated structures. It is the largest system in the human body and plays a crucial role in protecting and maintaining homeostasis. The integumentary system serves several functions including protection, regulation, sensation, and secretion.
The skin, which is the primary organ of the integumentary system, consists of three main layers: the epidermis, dermis, and hypodermis (subcutaneous tissue). The epidermis is the...
The skin, which is the primary organ of the integumentary system, consists of three main layers: the epidermis, dermis, and hypodermis (subcutaneous tissue). The epidermis is the...
17.4K
Staphylococcal Skin Infections
143
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
143


