Related Experiment Video
Updated: May 5, 2026

Detection of Anti-MDA5 Autoantibodies Using HeLa Cells and Immunocytochemistry with Light Microscopy
Published on: October 31, 2025
Myositis ossificans: the mimicker
Arunkumar Govindarajan1, Radha Sarawagi, Manikka Lakshmanan Prakash
1Department of Radiology, Mahatma Gandhi Medical College and Research Institute, Pondicherry, India.
This case study highlights myositis ossificans, a condition causing painful swelling and backache in adolescents. Imaging like CT scans confirmed the diagnosis by showing characteristic calcification development.
Area of Science:
- Radiology
- Orthopedic Surgery
- Pediatric Case Study
Background:
- Myositis ossificans is a benign condition involving heterotopic bone formation in muscle.
- Early diagnosis is crucial for appropriate management and to differentiate from malignant tumors.
Observation:
- A 14-year-old male presented with acute onset upper backache and a painful paraspinal swelling.
- Initial MRI revealed a non-specific lesion with intense enhancement.
- Ultrasound and CT demonstrated peripheral calcification evolving over time.
Findings:
- The imaging findings, particularly the progressive rim calcification on CT, were diagnostic of myositis ossificans.
- The case underscores the importance of serial imaging in diagnosing evolving musculoskeletal lesions.
- Differential diagnoses included soft tissue tumors and infections.
Implications:
- This case emphasizes the utility of advanced imaging techniques in diagnosing myositis ossificans.
- Understanding the imaging spectrum of myositis ossificans aids in accurate diagnosis and avoids unnecessary interventions.
- Further research into the pathogenesis and optimal treatment strategies for myositis ossificans is warranted.
More Related Videos
07:15In vivo Macrophage Imaging Using MR Targeted Contrast Agent for Longitudinal Evaluation of Septic Arthritis
Published on: October 20, 2013
09:17Minimally Invasive Muscle Embedding MIME - A Novel Experimental Technique to Facilitate Donor-Cell-Mediated Myogenesis
Published on: August 24, 2017
Related Concept Videos
Myasthenia Gravis: Diagnostic Tests
The edrophonium test is a diagnostic tool for myasthenia gravis. It involves...
Myocarditis II: Clinical Features and Diagnostic Tests
Disorders of the Skeletal Muscle
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Myasthenia Gravis ll: Pathophysiology
Myocarditis I: Introduction
Microscopic Anatomy of Skeletal Muscles
The muscle sarcolemma is a plasma membrane enclosing each muscle cell that conducts electrical signals called action potentials. The sarcolemma extends into the cell to form T-tubules, ensuring the neural impulses are uniformly distributed across the entire muscle...